Traditionally, proteins are described in a single static state (a picture). It is now increasingly recognised that many proteins can adopt multiple states and move between these conformational states dynamically (a movie). Even more, not every protein has a well-defined three-dimensional structure, many are partly or fully disordered. These predictions describe backbone and side-chain dynamics, disorder, early folding events, beta-sheet aggregation and phase separation.
Domains
Archaea, Bacteria, Eukaryota, Viruses
Kingdoms
Animals, Fungi, Heunggongvirae, Methanobacteriati, Pararnavirae, Plants, Pseudomonadati, Thermoproteati, Thermotogati
Proteomes
Atlas entries
Entry views
Choose an organism
Each proteome below comes from UniProt's reference proteomes and carries the same predictions, so results are comparable between species. Open a proteome for its profile and search, or go straight to its entry list.
Human Featured
Homo sapiens
Silhouette: PhyloPic (CC0 1.0) via PhyloPic, licence, retrieved 19 Aug 2026
Baker's yeast
Saccharomyces cerevisiae
Silhouette: Arcadia Science (CC0 1.0) via PhyloPic, licence, retrieved 19 Aug 2026
Escherichia coli (strain K12)
Escherichia coli
Silhouette: Arcadia Science (CC0 1.0) via PhyloPic, licence, retrieved 19 Aug 2026
Fruit fly
Drosophila melanogaster
Silhouette: Kamil S. Jaron (CC0 1.0) via PhyloPic, licence, retrieved 19 Aug 2026
Halophilic archaeon
Haloferax volcanii DS2
Silhouette: PhyloPic (CC0 1.0) via PhyloPic, licence, retrieved 19 Aug 2026
Human herpesvirus 4
Epstein–Barr virus, strain B95-8
Silhouette: Attribution 4.0 International (Ypna) via PhyloPic, licence, retrieved 20 Aug 2026
Human immunodeficiency virus type 1, isolate HXB2
Human immunodeficiency virus type 1, isolate HXB2
Silhouette: Arcadia Science (CC0 1.0) via PhyloPic, licence, retrieved 19 Aug 2026
Hyperthermophilic methanogen
Methanocaldococcus jannaschii JAL-1
Silhouette: PhyloPic (CC0 1.0) via PhyloPic, licence, retrieved 19 Aug 2026
Mouse
Mus musculus
Silhouette: Matthew Schmitz (CC0 1.0) via PhyloPic, licence, retrieved 19 Aug 2026
Pig
Sus scrofa
Silhouette: Gabriela Palomo-Munoz (CC BY 4.0) via PhyloPic, licence, retrieved 19 Aug 2026
Rat
Rattus norvegicus
Silhouette: Arcadia Science (CC0 1.0) via PhyloPic, licence, retrieved 19 Aug 2026
Roundworm
Caenorhabditis elegans
Silhouette: Arcadia Science (CC0 1.0) via PhyloPic, licence, retrieved 19 Aug 2026
Sulfolobus acidocaldarius
Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
Silhouette: Matt Crook (CC BY-SA 3.0) via PhyloPic, licence, retrieved 19 Aug 2026
Thale cress
Arabidopsis thaliana
Silhouette: Arcadia Science (CC0 1.0) via PhyloPic, licence, retrieved 19 Aug 2026
Thermus thermophilus HB8
Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
Silhouette: Matt Crook (CC BY-SA 3.0) via PhyloPic, licence, retrieved 19 Aug 2026
Western clawed frog
Xenopus tropicalis
Silhouette: PhyloPic (CC0 1.0) via PhyloPic, licence, retrieved 19 Aug 2026
Zebrafish
Danio rerio
Silhouette: Caleb M. Gordon (CC0 1.0) via PhyloPic, licence, retrieved 19 Aug 2026
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2
Sequence-based predictions for the characteristics of the proteins that compose the SARS-CoV-2 virus, which causes COVID-19.
Silhouette: Arcadia Science via PhyloPic, CC0 1.0, retrieved 17 Aug 2026. Betacoronavirus, the genus.
Most viewed proteins
What visitors are reading across every proteome in the atlas.
- 1 P52292 · KPNA2 Human 10 views
- 2 P04637 · TP53 Human 7 views
- 3 P0DMC2 · apela Zebrafish 5 views
- 4 P23572 · Cdk1 Fruit fly 5 views
- 5 A0A1B0GTB2 · TUNAR Human 4 views
- 6 A0A8M1NHK4 · rbm47 Zebrafish 4 views
- 7 B1V8A0 · unc-57 Roundworm 4 views
- 8 O13511 · YAL065C Baker's yeast 4 views
- 9 P03185 · NEC2 Human herpesvirus 4 4 views
- 10 P61254 · RPL26 Human 3 views
How it works
Every entry is a canonical UniProt sequence. Predictions are computed with b2bTools and shown per residue, alongside a 3D model where one exists.
- DynaMine
- backbone and side-chain dynamics
- DisoMine
- disorder
- EFoldMine
- early folding
- AgMata
- beta-sheet aggregation
- PSPer
- phase separation
Your own sequences
Not every protein is in a reference proteome. The Bio2Byte online predictors run these same five predictors on any sequence you give them — one sequence or an alignment — and return the same per-residue values you see here.
Use it from code
Entries, provenance and predictions are all available over a documented REST API — no key required.
New here?
The help page is a guided tour of the atlas — find a protein, read its entry, download the data — with the human tumour suppressor P53 as the worked example.