The Bio2Byte group is led by Prof. Dr. Wim Vranken, with many people contributing to the research


If you are interested in our work, keep an eye on the publications in which the lab has been involved.


For joining us, have a look at what possible opportunities we have.


The Bio2Byte group is primarily situated at the Interuniversity Institute of Bioinformatics in Brussels, a collaborative interfaculty institute between the Vrije Universiteit Brussel and the Université Libre de Bruxelles. It is located at the the ULB side of the Pleinlaan/La Plaine campus on the 6th floor of the C building.

At the VUB, the group is linked to Structural Biology Brussels at the Bioengineering sciences department, as well as the departments of Computer Science and Chemistry at the Faculty of Sciences, plus to the Biomedical sciences at the Faculty of Medicine and Pharmacy.


Our research is funded from various sources, listed below:
  • ProteinContour (Jan. 1, 2021-Dec. 12, 2024) from FWO

    In this project (FWO identifier G028821N), we combine mass spectrometry analysis expertise from UGent (CompOmics group, Lennart Martens) and UCL (Laurent Gatto) with our predictions to map the relationships between post-translational modifications, sub cellular location, interactions and biophysical features of proteins in human cells.

  • TumorScope (Oct. 1, 2019-Sept. 30, 2024) from VUB

    In this interdisciplinary research project (IRP) from the VUB, we leverage the unique expertise and data present at the VUB and the UZ Brussel to create a general framework to store and analyze raw medical data, both at the image and molecular level, in relation to solid tumors, their clinical behavior and response to therapies. An integrated research platform, which conforms to GDPR and patient legislation, will enable AI-driven extraction of new information on breast and brain tumors, as well as sarcomas. Combined with expert insights from clinicians, we will work towards assisting and improving the decision-making process in especially multi-disciplinary oncology consults (MOC).

  • RNAct (Jan. 1, 2019-Dec. 31, 2023) from EC

    The H2020-MSCA-ITN-2018 813239 RNAct project focusses on 'Enabling proteins with RNA recognition motifs for synthetic biology and bio-analytics'.

  • FWOESFRI2 (Nov. 6, 2017-Dec. 31, 2019) from ELIXIR-Belgium

    Bringing European standards to Brussels : Preparing the human health related (IB)2 services and databases for ELIXIR.

  • G.0328.16N (Jan. 1, 2016-Dec. 31, 2019) from FWO

    FoldMod - The role of local amino acid interactions in the folding of proteins, the stability of their fold and the location of post-translational modifications.

  • ICITY-RDI.BRU (Jan. 1, 2014-Dec. 31, 2023) from ICITY

    A software framework for identifying molecular causes of human diseases (Mutaframe)

  • Ph.D. grant Daniele Raimondi (Jan. 1, 2013-Dec. 31, 2017) from IWT

    Advancing the prediction and understanding of coding variant effects

  • BB2B 2010-1-12 (Dec. 1, 2010-Nov. 30, 2015) from Innoviris

    Brains Back to Brussels project - Combining experiment and informatics to study biopolymer dynamics and interactions.